A Patient with a Large Gastric Tumor and Protein-Losing Gastroenteropathy Successfully Treated with Neoadjuvant TS-1 Combined with CDDP Therapy

A Patient with a Large Gastric Tumor and Protein-Losing Gastroenteropathy Successfully Treated with Neoadjuvant TS-1 Combined with CDDP Therapy

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Gastric cancer with protein-losing gastroenteropathy is relatively rare worldwide.The most important problem for the treatment of these patients is their low nutritional status and protein level, which can cause severe postoperative complications.We report a 49-year-old Japanese female with a large gastric tumor and protein-losing gastroenteropathy successfully treated with neoadjuvant TS-1 combined with CDDP therapy.She had a type 5 tumor with partially cauliflower-like appearance.Her blood chemistry revealed luau thank you cards low serum total protein (3.

3 g/dl) and low albumin (1.7 g/dl).She was additionally diagnosed with protein-losing gastroenteropathy based on 99mTc-human serum albumin berkley power worm 100 pack scintigraphy.Initial neoadjuvant chemotherapy decreased the size of the tumor and led to a marked improvement in her serum protein levels.She then underwent a total gastrectomy and lymph node dissection (D2) with a combined resection of the spleen and gallbladder.

Therefore, neoadjuvant chemotherapy may provide a safe treatment before definitive surgery for gastric cancer with protein-losing gastroenteropathy.